Mechanism of heart-rate acceleration caused by stimulation of vagal centers in the frog
| Autor: | V. M. Smirnov |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Tachycardia
medicine.medical_specialty business.industry Stimulation General Medicine General Biochemistry Genetics and Molecular Biology Atropine Endocrinology Internal medicine Vagal escape Heart rate acceleration Heart rate medicine Medulla oblongata Benzohexonium medicine.symptom business medicine.drug |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 124:635-638 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf02445047 |
| Popis: | The mechanism by which heart rate is increased upon stimulation of vagal centers is studied using frog heart preparations perfused with Ringer—Locke solution containing atropine and/or benzohexonium. Atropine stimulates vagus-induced heart-rate acceleration in dilutions of 10−6 and 10−5 g/ml. In a dilution of 10−4 g/ml both atropine and benzohexonium abolish vagal tachycardia. Rausedyl (3–4 injections, 5 mg/kg, at 18–20-h interval) prevents tachycardia. Stimulation of both halves of the medulla oblongata increases heart rate to a greater extent than stimulation of one half. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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