Pharmacoeconomic Evaluation of Tegafur-Uracil (UFT) vs Fluorouracil for the Management of Colorectal Cancer in Brazil and Argentina

Autor: Neeta Sinha, Steven R. Arikian, Amit Sadana, Andre M. Murad, Christopher M. Dezii, Carlos Delfino, John Doyle, Carlos Augusto de Andrade
Rok vydání: 1997
Předmět:
Zdroj: Clinical Drug Investigation. 13:90-98
ISSN: 1173-2563
DOI: 10.2165/00044011-199713020-00005
Popis: The treatment of colorectal cancer continues to pose major challenges for oncologists throughout the world. Uracil and tegafur (UFT), as an oral agent, represents a new patient-focused approach to managing a malignancy with few treatment alternatives other than an intravenous fluorouracil (5-FU)-based regimen. The ability of UFT to achieve equivalent clinical outcomes compared with continuous 5-FU infusion, along with its oral formulation and mild toxicity profile, provide a compelling backdrop for fiscal analysis. An economic assessment of therapy attributes and effects would, therefore, be prudent and necessary when deliberating the adoption of this chemotherapy regimen.
Databáze: OpenAIRE