| Autor: |
Rajat Kumar, Maria Salas, Eshetu Atenafu, Ivan Pasic, Ora Bascom, Leeann Wilson, Wilson Lam, Arjun Law, Carol Chen, Igor Novitzky-Basso, Dennis Kim, Armin Gerbitz, Auro Viswabandya, Fotios Michelis, Jeffrey Lipton, Jonas Mattsson, Shabbir Alibhai |
| Rok vydání: |
2023 |
| Popis: |
The HCT Frailty Scale is an easy prognostic tool composed of (a) Clinical Frailty Scale; (b) Instrumental Activities of Daily Living; (c) Timed-up-and-Go test; (d) Grip Strength; (e) Self-Health Rated Questionnaire; (f) Falls tests; (g) Albumin and C-reactive protein levels. This scale was designed to classify allogeneic hematopoietic cell transplant (alloHCT) candidates into fit, pre-frail and frail groups, irrespective of age. This study evaluates the ability of this frailty classification to predict overall survival (OS) and non-relapse mortality (NRM) in adult patients of all ages, in a prospective sample of 298 patients transplanted between 2018 and 2020. At first consultation, 103 (34.6%) patients were fit, 148 (49.7%) pre-frail, and 47 (15.8%) were frail. The 2-year OS and NRM of the three groups were 82.9%, 67.4%, and 48.3% (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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