PS4 - 19. Expression of lipid genes, but not adipokine genes, in visceral adipose tissue is related to liver damage in obese individuals

Autor:	Marten H. Hofker, Marcel Wolfs, Bart van de Sluis, Jingyuan Fu, Timon W. van Haeften, Wim A. Buurman, Ann Driessen, Ciska Wijmenga, Lude Franke, Sander S. Rensen, Jan Greve, Ludger Scheja
Rok vydání:	2011
Předmět:	medicine.medical_specialty Cell signaling business.industry Adipose tissue macrophages Adipokine Adipose tissue Inflammation Lipid metabolism White adipose tissue medicine.disease Endocrinology Internal medicine Diabetes mellitus medicine medicine.symptom business
Zdroj:	Nederlands Tijdschrift voor Diabetologie. 9:103-103
ISSN:	1876-6242 1567-2743
DOI:	10.1007/s12467-011-0044-1
Popis:	Obesity increases the risk to develop liver steatosis, inflammation, and consequently severe liver damage. This risk is associated with an increased flow of lipids and signaling molecules (adipokines), secreted by adipose tissue, through the liver. However, the relevance of lipids and adipokines in this crosstalk between adipose tissue and liver in obesity-related liver pathology is largely unknown. Therefore we investigated to what extend the expression of genes involved in lipid metabolism and adipokine genes in visceral adipose tissue is correlated to liver pathology in obese individuals.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f122d62014e7a560f815b6637fa38425 https://doi.org/10.1007/s12467-011-0044-1 Zobrazit plný text záznamu Full text from SpringerLink