An Unusual Case of Acute Muscle Weakness
| Autor: | Asjid Qureshi, Jacob F de Wolff, Edouard Mills, Suzanne R Harrogate |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Tachycardia
Unusual case Proximal muscle weakness business.industry Urinary retention Muscle weakness Thyrotoxic periodic paralysis General Medicine Critical Care and Intensive Care Medicine medicine.disease Anesthesia Emergency Medicine Internal Medicine medicine Proximal weakness Euthyroid medicine.symptom business |
| Zdroj: | Acute Medicine Journal. 15:209-211 |
| ISSN: | 1747-4884 |
| DOI: | 10.52964/amja.0638 |
| Popis: | A previously healthy 35-year old man presented to hospital with acute leg weakness following an alcohol binge. On assessment, tachycardia, urinary retention and bilateral upper and lower limb proximal weakness with preserved peripheral power were noted. Biochemistry revealed marked hypokalaemia, which responded to intravenous replacement, and biochemical thyrotoxicosis, leading to the diagnosis of Thyrotoxic Periodic Paralysis (TPP). Anti-thyroid therapy and beta-blockers were commenced and his neurological symptomatology resolved as he became progressively euthyroid. TPP is a rare acquired subtype of hypokalaemic periodic paralysis, typically causing proximal muscle weakness associated with thyrotoxicosis. It is most common in young Asian males. Acute treatment requires cautious oral potassium supplementation, beta-blockade, and anti-thyroid therapy. TPP is prevented by maintaining euthyroidism; otherwise recurrence is likely. |
| Databáze: | OpenAIRE |
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