Effect of Shock Waves Generated by Pulsed Electric Discharges in Water on Yeast Cells and Virus Particles
| Autor: | A. N. Gorshkov, Vladimir V. Egorov, V. A. Kolikov, V. N. Snetov, G. A. Shneerson, A. E. Girdyuk |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Shock wave Materials science 030102 biochemistry & molecular biology Physics and Astronomy (miscellaneous) Pulse (signal processing) Pulse duration Cell morphology 01 natural sciences Electric charge Molecular physics Yeast Quantitative Biology::Cell Behavior 010305 fluids & plasmas 03 medical and health sciences Amplitude 0103 physical sciences Current (fluid) |
| Zdroj: | Technical Physics. 63:285-290 |
| ISSN: | 1090-6525 1063-7842 |
| DOI: | 10.1134/s1063784218020159 |
| Popis: | The aim of this study is to determine the optimal parameters of the electric pulses and shock waves generated by them for the soft destruction of the virus and yeast envelopes with no changes in the structure of antigenic surface albumin and in the cell morphology in order to use them to produce antivirus vaccines and in biotechnology. The pulse electric discharges in water have been studied for different values of amplitude, pulse duration and the rate of the rise in the current. A mathematical model has been developed to estimate the optimal parameters of pulsed electric charges and shock waves for the complete destruction of the yeast cell envelopes and virus particles at a minimum of pulses. |
| Databáze: | OpenAIRE |
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