Does Colectomy Improve Type 2 Diabetes?

Autor: Scott R. Steele, Ali Aminian, Roman Vangoitsenhoven, Tracy L. Hull, Philip R. Schauer, Suriya Punchai, Rickesha Wilson, Zubaidah Nor Hanipah, Katherine M Meister
Rok vydání: 2020
Předmět:
Zdroj: Obesity Surgery. 30:2429-2433
ISSN: 1708-0428
0960-8923
DOI: 10.1007/s11695-019-04346-w
Popis: Gastrectomy and gastric bypass improve type 2 diabetes (T2DM), potentially through alterations in intestinal hormones and the microbiome. The aim of this study was to analyze whether colorectal resections result in improvement of T2DM. A total of 171 patients with T2DM who underwent colectomy for benign diseases were studied with a median postoperative follow-up of 3 years (interquartile range [IQR] 1–5). The median BMI and glycated hemoglobin (HbA1c) at baseline and post-colectomy were 30.3 kg/m2 (IQR 26.6–34.6) versus 30.4 kg/m2 (IQR 26.2–35) (p = 0.1), and 6.7% (IQR 6.2–7.5) versus 6.5% (IQR 6.5–7.1) (p = 0.5), respectively. The proportion of patients taking diabetes medications at baseline versus post-colectomy did not differ significantly. Changes in BMI, HbA1c, and status of diabetes medications were not statistically different between the subtypes of colorectal resection. Our experience suggests that colectomy for benign colorectal diseases is not associated with long-term changes in body weight or glycemic control.
Databáze: OpenAIRE
Externí odkaz: