Bullous Diseases: Old Blisters with New Therapeutic Targets

Autor: Michael Hertl, Rüdiger Eming, Kyle T. Amber
Rok vydání: 2015
Předmět:
Zdroj: Personalized Treatment Options in Dermatology ISBN: 9783662458396
Popis: Immunobullous diseases are rare but potentially life threatening diseases that often require aggressive immunosuppression. While traditionally this has been in the form of broad immunosuppression with small-molecule drugs such as corticosteroids, newer therapies have arisen, targeting more specific pathways in the immunopathogenesis of the disease. We discuss the use of immunoadsorption, intravenous immunoglobulin, and rituximab in different bullous diseases, as well as the underlying mechanism behind these drugs.
Databáze: OpenAIRE