Hematopoietic tissue reactions associated with growth of syngeneic transplantable tumors in mice
| Autor: | V. M. Bukhman, T. V. Osipova, G. Ya. Svet-Moldavskii, N. I. Belyanchikova |
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| Rok vydání: | 1978 |
| Předmět: |
Hemangiopericytoma
Pathology medicine.medical_specialty Hematopoietic Tissue Spleen General Medicine Biology medicine.disease General Biochemistry Genetics and Molecular Biology Haematopoiesis medicine.anatomical_structure medicine Bone marrow Leukocytosis Myelopoiesis medicine.symptom Leukemoid reaction |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 85:372-375 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf00801362 |
| Popis: | Hemangiopericytoma growth in syngeneic male mice F1 (CBA X C57BL/bj) led to regular hemopoietic changes: an increase in the spleen weight, spleen cell count, in the number of colony-forming units (CFU). It also induced augmentation of myelopoiesis in the spleen and leukocytosis with a sharp increase of segmented granulocytes in the circulating blood characterized as the "leukemoid reaction" syndrome. The latter occurred even when the tumour cells were transplanted into the splenectomized host. Although less marked, this leukemoid reaction was also noted in advanced hepatoma transplanted to syngeneic male mice F1 (CBA X C57BL/6j). No leukemoid reaction was observed in these mice after grafting syngeneic strain of urinary bladder carcinoma. |
| Databáze: | OpenAIRE |
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