Diagnostic pitfalls of thyroid pathology

Autor:	Manuel Sobrinho-Simões, Elsa Fonseca, J.F Magalhaes, Isabel Amendoeira
Rok vydání:	2005
Předmět:	Pathology medicine.medical_specialty Thyroid pathology business.industry Thyroid Cytogenetics medicine.disease Pathology and Forensic Medicine medicine.anatomical_structure medicine Immunohistochemistry Papillary carcinoma Differential diagnosis business Thyroid cancer Solid Growth Pattern
Zdroj:	Current Diagnostic Pathology. 11:52-59
ISSN:	0968-6053
DOI:	10.1016/j.cdip.2004.07.007
Popis:	Summary The huge amount of information carried to the field of thyroid oncology by immunohistochemistry, cytogenetics and molecular biology did not solve (yet?) the most frequent dilemmas faced by surgical pathologists when dealing with thyroid lesions: differential diagnosis of encapsulated, follicular-patterned tumours with less-than-typical nuclei and equivocal signs of invasiveness; classification of oncocytic (Hurthle cell) tumours; identification of poorly differentiated carcinomas in the background of papillary carcinomas with foci of solid growth pattern and of widely invasive follicular carcinomas; and, finally, cytological and histological diagnosis of metastatic lesions. This review is intended to point out the diagnostic pitfalls in the aforementioned settings and to provide some strategies to deal with them in a practical way.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f0a512e98694926596fd802e414a67e5 https://doi.org/10.1016/j.cdip.2004.07.007 Zobrazit plný text záznamu Full Text from ScienceDirect