Enzymatic conversion of cholest-8(14)-en-3β,15α-diol and cholest-8(14)-en-3β,15β-diol to cholesterol
Autor: | S. Huntoon, G.J. Schroepfer |
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Rok vydání: | 1970 |
Předmět: | |
Zdroj: | Biochemical and Biophysical Research Communications. 40:476-480 |
ISSN: | 0006-291X |
DOI: | 10.1016/0006-291x(70)91033-8 |
Popis: | Reduction of 3β-benzoyloxy-cholest-8(14)-en 13-one with lithium aluminum hydride yielded two epimers (at C-15) of cholest-8(14)-en-3β,15-diol. Reduction with lithium aluminum tritide yielded [15α-3H]-cholest-8(14)-en-3β,15β-diol and [15β-3H]-cholest-8(14)-en-3β,155-diol. Both labeled compounds served as efficient substrates for cholesterol formation in rat liver homogenate preparations. |
Databáze: | OpenAIRE |
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