Enzymatic conversion of cholest-8(14)-en-3β,15α-diol and cholest-8(14)-en-3β,15β-diol to cholesterol

Autor: S. Huntoon, G.J. Schroepfer
Rok vydání: 1970
Předmět:
Zdroj: Biochemical and Biophysical Research Communications. 40:476-480
ISSN: 0006-291X
DOI: 10.1016/0006-291x(70)91033-8
Popis: Reduction of 3β-benzoyloxy-cholest-8(14)-en 13-one with lithium aluminum hydride yielded two epimers (at C-15) of cholest-8(14)-en-3β,15-diol. Reduction with lithium aluminum tritide yielded [15α-3H]-cholest-8(14)-en-3β,15β-diol and [15β-3H]-cholest-8(14)-en-3β,155-diol. Both labeled compounds served as efficient substrates for cholesterol formation in rat liver homogenate preparations.
Databáze: OpenAIRE