| Autor: |
Remzi Önder, Bülent Kiliçcioglu, Istemi Nalbantgil, Mehmet Işler |
| Rok vydání: |
1993 |
| Předmět: |
|
| Zdroj: |
Current Therapeutic Research. 53:621-629 |
| ISSN: |
0011-393X |
| DOI: |
10.1016/s0011-393x(05)80732-5 |
| Popis: |
The antihypertensive effect of amlodipine was investigated in 20 patients (11 men and nine women) with essential hypertension using 24-hour monitoring of ambulatory blood pressure. The patients received placebo initially for 1 week followed by amlodipine 5 mg/day for 8 weeks. In three patients whose diastolic blood pressure did not fall below 90 mmHg after 4 weeks, the dosage was raised to 10 mg/day. All patients underwent ambulatory blood pressure monitoring at the end of the placebo period and at the end of 8 weeks of active treatment. Blood pressures and heart rate were measured and a physical examination was performed every 2 weeks during the treatment period. By the second week of treatment, systolic and diastolic blood pressures were significantly reduced with amlodipine therapy ( P P P P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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