p-Toluenesulfonic acid-catalyzed regioselective C4–H iodination of isoquinolin-1(2H)-ones

Autor: Cai-Yun Yang, Lin-Ping Hu, De-Run Zhang, Xia Li, Ming-Yu Teng, Bo Liu, Guo-Li Huang
Rok vydání: 2022
Předmět:
Zdroj: New Journal of Chemistry. 46:10934-10939
ISSN: 1369-9261
1144-0546
DOI: 10.1039/d2nj00159d
Popis: An efficient procedure for p-toluenesulfonic acid-catalyzed iodination of isoquinolin-1(2H)-ones with N-iodosuccinimide under mild reaction conditions is reported. This methodology features scalable synthesis, wide substrate scope, and high functional-group tolerance.
Databáze: OpenAIRE