Lipid Peroxidation State in Women of Reproductive Age with Acute Form of Viral Hepatitis

Autor:	O. A. Vanteeva, Lyudmila Grebenkina, L. F. Sholokhov, M. A. Rashidova, Marina Darenskaya, Lyubov Kolesnikova
Rok vydání:	2016
Předmět:	Hepatitis Very low-density lipoprotein business.industry Physiology Reproductive age General Medicine Superoxide dismutase activity medicine.disease Lipid peroxidation chemistry.chemical_compound chemistry medicine In patient Viral hepatitis business Lipoprotein cholesterol
Zdroj:	Annals of the Russian academy of medical sciences. 71:11-15
ISSN:	2414-3545 0869-6047
DOI:	10.15690/vramn525
Popis:	Objective: The objective of this study was to identify features of the lipid status and lipid peroxidation-antioxidant defense system in women of reproductive age with acute form of hepatitis. Methods: The study involved 36 women with acute viral hepatitis and 28 healthy women of the same age. Spectrophotometric and fluorometric methods were used. Results: In patients with acute viral hepatitis we detected an increase in triglycerides levels ― by 21% and very low density lipoprotein values — by 17% in relative to control group, high-density lipoprotein cholesterol content reduced by 38%. In group with acute viral hepatitis the TBA-reactive products level increased by 2.21 times and superoxide dismutase activity decreased by 1.43 times in comparison with control group. Conclusion: The acute form of hepatitis is characterized by series of metabolic disorders that require a more careful approach in therapeutic and diagnostic administration.
Databáze:	OpenAIRE
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