| Autor: |
A. N. Howard, A. G. Archer, K. E. Earle, J E Baillie |
| Rok vydání: |
1988 |
| Předmět: |
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| Zdroj: |
Trace Elements in Man and Animals 6 ISBN: 9781461280507 |
| DOI: |
10.1007/978-1-4613-0723-5_168 |
| Popis: |
The possibility of an altered chromium metabolism in subjects with diabetes has been a topic of discussion for many years. The aims of this study were (a) measure the plasma chromium profile and excretion following a glucose challenge in controls, non-insulin dependent (NIDD) and insulin dependent diabetics (IDD), (b) observe the effect of obesity, (c) assess the effect of hypoglycaemic drugs on chromium. Subjects included 34 controls, 22 NIDD’s and 23 IDD’s. Groups subdivided by BMI; BMI 30 as obese. Food and drugs were withdrawn overnight and fasting urine was collected prior to the test. 75g glucose were given and blood collected every 30 mins. for 3 hrs. Urine was collected for 4 hrs. post glucose. Chromium was analysed by EAAS. Lean controls had significantly lower plasma chromium and insulin than oljese controls at all time points except zero (1hr; 0.66±0.35 vs 1.16±0.69ng.m1−1, p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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