Metabolism of Phenothiazine and Butyrophenone Antipsychotic Drugs
| Autor: | John W. Hubbard, Edward M. Hawes, Manickam Aravagiri, Kamal K. Midha, Gordon McKay, E. D. Korchinski, Stephen R. Marder |
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| Rok vydání: | 1993 |
| Předmět: |
Drug
medicine.medical_specialty Psychosis Butyrophenone Metabolite media_common.quotation_subject medicine.medical_treatment Pharmacology 03 medical and health sciences Route of administration chemistry.chemical_compound 0302 clinical medicine Pharmacokinetics Phenothiazine medicine 030212 general & internal medicine Psychiatry Antipsychotic media_common business.industry food and beverages medicine.disease 030227 psychiatry Psychiatry and Mental health chemistry business |
| Zdroj: | British Journal of Psychiatry. 163:19-24 |
| ISSN: | 1472-1465 0007-1250 |
| Popis: | Whereas some metabolites of antipsychotic drugs are psychoactive and contribute to clinical improvement, recent studies have provided evidence that certain metabolites contribute to side-effects which can be disabling enough to negate clinical improvement as regards the psychosis. The route of administration of the drug can determine the amount of metabolite produced in the body and affect how the patient feels in response to the treatment. |
| Databáze: | OpenAIRE |
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