The synthesis of 2-substituted-1,4-dihydropyridines

Autor: David Alker, S. M. Denton
Rok vydání: 1990
Předmět:
Zdroj: Tetrahedron. 46:3693-3702
ISSN: 0040-4020
DOI: 10.1016/s0040-4020(01)81539-8
Popis: Reaction of the 2-hydroxymethyl-1,4-dihydropyridines 7 and 13 with SO2Cl2limidazole followed by treatment with nucleophiles affords 2-substituted-l,4-dihydropyridines via the intermediacy of the 2-chloromethyl compounds 14 and 18, respectively.
Databáze: OpenAIRE