Reaction of quinine, 9-epiquinine and their acetates in superacid in the presence of hydrogen peroxide: an access to new fluorhydrins and/or ketones
Autor: | Marie-Paule Jouannetaud, Jean-Claude Jacquesy, Vincent Chagnault |
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Rok vydání: | 2006 |
Předmět: | |
Zdroj: | Tetrahedron Letters. 47:5723-5726 |
ISSN: | 0040-4039 |
Popis: | In HF–SbF 5 , in the presence of H 2 O 2 (source of OH + equivalent) quinine 1a yields 10-keto derivatives 4a and 5a and cyclic ether 3 as the major product. In the same conditions 1b , 2a , and 2b give the 10-keto and 10-fluoro-3-hydroxy analogs. |
Databáze: | OpenAIRE |
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