Role of radiotherapy in the treatment of metastatic head and neck cancer
| Autor: | Jaime Gómez-Millán, Rafael Ordóñez, Yolanda Lupiañez-Perez, Inmaculada Jerez, Ana Otero, J. A. Medina |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Oncology medicine.medical_specialty Chemotherapy business.industry medicine.medical_treatment Head and neck cancer Retrospective cohort study Disease medicine.disease Primary tumor Radiation therapy 03 medical and health sciences Regimen 030104 developmental biology 0302 clinical medicine Quality of life 030220 oncology & carcinogenesis Internal medicine medicine Pharmacology (medical) business |
| Zdroj: | OncoTargets and Therapy. 12:677-683 |
| ISSN: | 1178-6930 |
| DOI: | 10.2147/ott.s181697 |
| Popis: | In metastatic or locally advanced head and neck tumors that present in frail patients or after chemotherapy progression, radiotherapy is normally used as a palliative treatment, with a high rate of symptom palliation and improvement in quality of life. However, there is controversy about what the optimal regimen is. Moreover, despite the poor prognosis of metastatic head and neck cancer, different retrospective studies have shown that a minority of patients with oligometastatic disease experience prolonged disease-free survival after adding curative radiotherapy treatment to the metastatic disease and/or primary tumor. Different retrospective studies have identified clinical prognostic factors that may be used to select candidate patients with metastatic head and neck cancer for a radical approach with radiotherapy. The purpose of this manuscript is to review the role of radiotherapy in metastatic and locally advanced head and neck tumors. |
| Databáze: | OpenAIRE |
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