Post-ligation cardiac syndrome is associated with increased morbidity in preterm infants
| Autor: | Kimberly J. Reid, Taylor P Hansen, Michael A. Bingler, Timothy J. B. Ulrich, Steven L Olsen |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
congenital
hereditary and neonatal diseases and abnormalities Pediatrics medicine.medical_specialty business.industry Obstetrics and Gynecology Retrospective cohort study Retinopathy of prematurity macromolecular substances 030204 cardiovascular system & hematology medicine.disease 03 medical and health sciences 0302 clinical medicine Increased risk medicine.anatomical_structure Primary outcome Neonatal outcomes 030225 pediatrics Ductus arteriosus Pediatrics Perinatology and Child Health medicine business Complication Ligation |
| Zdroj: | Journal of Perinatology. 38:537-542 |
| ISSN: | 1476-5543 0743-8346 |
| DOI: | 10.1038/s41372-018-0056-4 |
| Popis: | The influence of post-ligation cardiac syndrome (PLCS), a complication of patent ductus arteriosus (PDA) ligations, on neonatal outcomes is unknown. The purpose of this study was to determine the risks of PLCS on severe pulmonary morbidity and severe retinopathy of prematurity (ROP). Retrospective cohort study of infants who underwent a PDA ligation between 2006 and 2015. Data were collected on patients with and without PLCS. The primary outcome was the difference in severe bronchopulmonary dysplasia (BPD) between groups. Secondary outcomes included discharge with home oxygen and severe ROP. A total of 100 infants that underwent PDA ligation during the study period were included in the study; 31 (31%) neonates developed PLCS. In adjusted analysis, PLCS was associated with increased risk for severe BPD (RR 1.67, 95% CI: 1.15–2.42) and home oxygen therapy (RR: 1.47, 95% CI: 1.09–1.99) only. No association with severe ROP was seen (RR: 1.48; 95% CI: 0.87–2.52). PLCS is associated with severe neonatal pulmonary morbidity, but not with severe ROP. Further investigation is warranted to validate these results. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink