Straightforward synthesis of benzoxazoles and benzothiazoles via photocatalytic radical cyclization of 2-substituted anilines with aldehydes

Autor:	Hai Truong Nguyen, Quynh Nhu Ba Nguyen, Hao Anh Nguyen Le, Phuong Hoang Tran, Khang Quoc Nguyen, Long Hoang Nguyen
Rok vydání:	2020
Předmět:	Reaction conditions Eosin 010405 organic chemistry Process Chemistry and Technology General Chemistry 010402 general chemistry 01 natural sciences Radical cyclization Combinatorial chemistry Catalysis 0104 chemical sciences chemistry.chemical_compound chemistry Photocatalysis Eosin Y
Zdroj:	Catalysis Communications. 145:106120
ISSN:	1566-7367
DOI:	10.1016/j.catcom.2020.106120
Popis:	Eosin Y-catalyzed one-pot coupling and cyclization of o-substituted anilines with aldehydes to form benzoxazoles and benzothiazoles under mild condition has been developed. The reaction scope was broadly tolerant of various 2-substituted anilines and aldehydes. The desired products were obtained in high yields with the use of eosin Y as a photocatalyst under a substantial refinement of reaction conditions in comparison with previous literature. Based on the experimental results observed, a plausible mechanism involving a radical process has been proposed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f034cd31de016faadf2fcd2e5170ebf1 https://doi.org/10.1016/j.catcom.2020.106120 Zobrazit plný text záznamu Full Text from ScienceDirect