Drug Treatment of Depression
| Autor: | Candace S. Brown, Stephen G. Bryant |
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| Rok vydání: | 1990 |
| Předmět: | |
| Zdroj: | Journal of Pharmacy Practice. 3:252-261 |
| ISSN: | 1531-1937 0897-1900 |
| DOI: | 10.1177/089719009000300407 |
| Popis: | The major advantage of the new generation of antidepressants lies in their enhanced ability to avoid unwanted side effects, such as anticholinergic or cardiovascular toxicities, and in many cases, to reduce fatalities after overdose. Second-generation antidepressants are as effective as the first generation agents, but are more selective, enabling precise targeting of symptoms. Caution in recommending the newer antidepressants must be applied, however, because these agents possess differing side effects, and unforeseen toxicities may not appear until after several years of use. Conventional tricyclics should not be overlooked in managing the depressed patient. This article discusses the symptoms of major depression, followed by the latest information on second-generation antidepressants. It concludes by providing the pharmacist with guidelines for when to select a newer over an older agent. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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