Investigation of necessary conditions for imaging cell analysis using EIT

Autor: Gregor Schulte, Holger Schönherr, Birgyl Veckollari, Müller Mareike, Christian Gibas, Rainer Brück
Rok vydání: 2019
Předmět:
Zdroj: Medical Imaging: Biomedical Applications in Molecular, Structural, and Functional Imaging
DOI: 10.1117/12.2512404
Popis: Electrical Impedance Tomography (EIT) is a method used to record the impedance distribution within a target. The best-known application of EIT is lung diagnostics using imaging algorithms. However, apart from this, there are individual research projects dealing with imaging analysis at the cellular level. For example, cell analysis using EIT can help to distinguish diseased cells from healthy cells. To achieve this goal, an existing EIT system was combined with a new EIT chip in a first step. This chip allows analysis in very small dimensions. Various parameters such as the diameter of the measuring environment, the necessary conductive solutions or the measuring methods used were varied and evaluated. In a next step, various image reconstructions were carried out using data acquired with C. elegans.
Databáze: OpenAIRE