Enantioselective Hydrogenation of Olefins Enhanced by Metal-Organic Framework Additives

Autor: Marco Ranocchiari, Beáta Vilhanová, Jeroen A. van Bokhoven
Rok vydání: 2015
Předmět:
Zdroj: ChemCatChem. 8:308-312
ISSN: 1867-3880
DOI: 10.1002/cctc.201500907
Popis: The use of nonprotic solvents (e.g., dichloromethane, toluene) increases the enantioselectivity of the asymmetric hydrogenation of olefins with chiral [Rh(Me-BPE)(cod)]OTf [Me-BPE=1,2-bis(2,5-dimethylphospholano)ethane; cod=1,5-cyclooctadiene; OTf=triflate]. Readily available achiral metal–organic frameworks (MOFs) as additives yielded substantially enhanced reactivity. In toluene (but not dichloromethane), the MOFs adsorbed the homogeneous catalyst, which directly reduced rhodium contamination in the products of the reaction. The in situ formed heterogeneous catalyst was reused without loss in selectivity.
Databáze: OpenAIRE