TRANSPLANTATION AND CELLULAR ENGINEERING: Association of stress-related perinatal factors and cord blood unit hematopoietic progenitors is dependent on delivery mode

Autor:	Sari Juutistenaho, Mikko Eskola, Kari Aranko, Susanna Sainio, Riitta Kekomäki
Rok vydání:	2009
Předmět:	Vaginal delivery business.industry Birth weight Immunology CD34 Hematology Delivery mode Umbilical cord Andrology Haematopoiesis medicine.anatomical_structure Cord blood medicine Immunology and Allergy Progenitor cell business
Zdroj:	Transfusion. 50:663-671
ISSN:	0041-1132
DOI:	10.1111/j.1537-2995.2009.02467.x
Popis:	BACKGROUND: Perinatal characteristics, variably utilized in cord blood (CB) selection for banking, affect CB hematopoietic progenitor cells (HPCs). The association between perinatal stress factors and CB unit HPCs was evaluated. STUDY DESIGN AND METHODS: Umbilical arterial (UA) pH, absolute and relative birth weight (BW) and placental weight (PW), and PW/BW ratio of 167 healthy, full-term infants were compared with CB unit prefreeze total nucleated cells (TNCs), total CD34+ (TCD34+) cells, and total colony-forming unit (CFU-TOT) number. Cesarean section (C-section, n = 104) and vaginal delivery subgroups were also analyzed. RESULTS: UA pH (median, 7.28; range, 7.04-7.40) correlated with CB unit CFU-TOT number (n = 166; r = −0.32, p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f00cf9d49493a3ba28533bc636adcd9e https://doi.org/10.1111/j.1537-2995.2009.02467.x Zobrazit plný text záznamu Plný text