Multislice perfusion and perfusion territory imaging in humans with separate label and image coils

Autor: Lawrence L. Wald, Timothy G. Reese, Greg Zaharchuk, Patrick J. Ledden, Bruce R. Rosen, Kenneth K. Kwong
Rok vydání: 1999
Předmět:
Zdroj: Magnetic Resonance in Medicine. 41:1093-1098
ISSN: 1522-2594
0740-3194
DOI: 10.1002/(sici)1522-2594(199906)41:6<1093::aid-mrm4>3.0.co;2-0
Popis: An arterial spin labeling technique using separate RF labeling and imaging coils was used to obtain multislice perfusion images of the human brain at 3 T. Continuous RF irradiation at a peak power of 0.3 W was applied to the carotid arteries to adiabatically invert spins. Labeling was achieved without producing magnetization transfer effects since the B1 field of the labeling coil did not extend into the imaging region or couple significant power into the imaging coil. Eliminating magnetization transfer allowed the acquisition of multislice perfusion images of arbitrary orientation. Combining surface coil labeling with a reduced RF duty cycle permitted significantly lower SAR than single coil approaches. The technique was also found to allow selective labeling of blood in either carotid, providing an assessment of the artery’s perfusion territory. In normal subjects, these territories were well-defined and localized to the ipsilateral hemisphere. Magn Reson Med 41:1093‐1098, 1999. r 1999 Wiley-Liss, Inc.
Databáze: OpenAIRE