Red Blood Cell Model Validation in Dynamic Regime
Autor: | Kristina Kovalcikova, Alžbeta Bohiniková, Ivan Cimrák, Isabelle Mazza Guimarães, Martin Slavík |
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Rok vydání: | 2018 |
Předmět: |
Work (thermodynamics)
Microchannel Materials science Microfluidics 02 engineering and technology Mechanics Deformation (meteorology) 021001 nanoscience & nanotechnology 01 natural sciences 010305 fluids & plasmas Model validation Red blood cell medicine.anatomical_structure Flow velocity 0103 physical sciences medicine Laboratory experiment 0210 nano-technology |
Zdroj: | Bioinformatics and Biomedical Engineering ISBN: 9783319787220 IWBBIO (1) |
DOI: | 10.1007/978-3-319-78723-7_22 |
Popis: | Our work is set in the area of microfluidics, and deals with behavior of fluid and blood cells in microfluidic devices. The aim of this article is to validate our numerical model of red blood cell. This is done by comparing computer simulation with existing laboratory experiment. The experiment is exploring the velocity and deformation of blood cells in a hyperbolic microchannel. Our research confirms that the deformation of the red blood cell in the simulation is comparable with the results from the experiment, as long as the fluid velocity profile in the simulation fits the fluid velocity profile of the experiment. This validates the elastic parameters of the red blood cell model. |
Databáze: | OpenAIRE |
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