ChemInform Abstract: Enantioselective Formal Synthesis of Nectrisine Using a Palladium-Catalyzed Asymmetric Allylic Amination and Cross-Metathesis as Key Steps

Autor:	Yolanda Díaz, Mariam Azzouz, M. Isabel Matheu, Sergio Castillón, Patricia Marcé, Sebastien Soriano, Josep Llaveria
Rok vydání:	2016
Předmět:	Allylic rearrangement Nectrisine chemistry Dihydroxylation Enantioselective synthesis chemistry.chemical_element General Medicine Metathesis Combinatorial chemistry Amination Palladium Catalysis
Zdroj:	ChemInform. 47
ISSN:	0931-7597
DOI:	10.1002/chin.201645183
Popis:	A formal enantioselective synthesis of nectrisine, a potent α-glucosidase inhibitor, was carried out starting from butadiene monoepoxide through a synthetic sequence involving enantioselective allylic substitution, cross-metathesis, dihydroxylation, and cyclization.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::efb9c67391cf29fa60f7ea79966dd440 https://doi.org/10.1002/chin.201645183 Zobrazit plný text záznamu Plný text