Nachweis des Epstein-Barr-Virus in Tonsillen bei infektiöser Mononukleose
| Autor: | J. Schneider, Renate Swoboda, Andreas Sauerbrei, I. Färber, Peter Wutzler |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Mononucleosis
medicine.diagnostic_test biology medicine.disease_cause medicine.disease Immunofluorescence biology.organism_classification Epstein–Barr virus Virology Herpesviridae Virus medicine.anatomical_structure stomatognathic system Otorhinolaryngology Antigen hemic and lymphatic diseases Tonsil medicine Gammaherpesvirinae |
| Zdroj: | Laryngo-Rhino-Otologie. 69:70-73 |
| ISSN: | 1438-8685 0935-8943 |
| DOI: | 10.1055/s-2007-998145 |
| Popis: | Tonsils of 50 patients with infectious mononucleosis were examined for the presence of Epstein-Barr virus nuclear antigens (EBNA) and in 11 cases for the presence of Epstein-Barr virus (EBV) nucleic acid sequences. In tonsillar tissue of 42 patients less than 1 to 40 per cent EBNA-positive cells could be demonstrated by anticomplement immunofluorescence. 10 out of 11 tonsils examined by in situ hybridization contained less than 1 to 50 per cent cells with EBV nucleic acid sequences. The histological examination indicated that cells labelled by in situ hybridisation are in the majority proliferating B-lymphocytes and to a small extent cells of tonsillar epithelium. |
| Databáze: | OpenAIRE |
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