| Popis: |
Excessive parathyroid secretion, such as occurs with parathyroid adenomas, causes a drain of lime salts from the body resulting in skeletal changes classified as Recklinghausen's disease or generalized osteitis fibrosa cystica. The negative calcium and phosphorus balance is commonly associated with hypercalcuria, hypercalcemia and hypophosphatemia and with skeletal, renal and gastro-intestinal symptoms that together constitute the classic form of hyperparathyroidism. The differentiation of this disease from others involving the bones is important because surgical removal of parathyroid adenomas is usually followed by extraordinary improvement if carried out before advanced skeletal deformities or renal impairment preclude complete restitution of the patient. The differential diagnosis of hyperparathyroidism may be difficult, however. The onset of the disease is usually insidious, the early manifestations are extremely varied, aberrations from the classic picture are common and the most characteristic features may be closely simulated by other diseases involving the bones. In this study, the problems |
