Onkologische Erkrankungen bei Jugendlichen und jungen Erwachsenen - Zahlen aus dem Klinischen Krebsregister Rostock als Arbeitsgrundlage für eine interdisziplinäre Herausforderung
| Autor: | Inken Hilgendorf, J. Klasen, C. F. Classen, S. Hartmann, P. Kropp, M. Freund, H. Zettl, S. Klöcking, D. Krogmann, A. Daunke |
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| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | TumorDiagnostik & Therapie. 32:85-92 |
| ISSN: | 1439-1279 0722-219X |
| Popis: | BACKGROUND: Adolescents and young adults represent a minority among cancer patients. In contrast to younger or older patients, their overall survival did not improve considerably in the last two decades. It is unknown whether this is due to different tumour biology or therapy concepts, or to particular psychosocial conditions in this age group, leading to reduced compliance or quality of care. Thus, the therapy of cancer in adolescents and young adults represents a particular challenge. In order to establish new concepts for the interdisciplinary therapy, in the following study all patients from 15 to 39 years of age reported to the clinical cancer registry Rostock in the last ten years were analysed. RESULTS: With an estimated reporting rate of 93 per cent, 2164 cases from a region of about 570 000 inhabitants were collected. The cancer incidence increases from each age cohort to the next: less than 5 % were 15 - 19 years old, more than 40 % 35 - 39 years. The distribution pattern of diagnoses changed continuously: In the youngest cohort, hematolymphatic diseases, brain tumours and sarkomas predominated, in the middle age cohort we saw a large number of melanomas and tumours of the inner female genitalia, and only in the high age cohort carcinomas outside the genitalia appeared more commonly, still representing a minority. Especially, the carcinomas in situ of the cervix uteri in young women included about one fourth of the whole patient group. Although, as expected, the large hospitals of the region predominated in reporting and therapy of the patients, about 40 per cent of the young patients were reported by physicians outside the hospitals, or by hospitals distant to the home regions of the patients. CONCLUSIONS: Adolescents and young adults show both biological and psychosocial differences compared to children and older adults. To better meet these challenges, new interdisciplinary concepts of therapy and care are needed. This study shows that treatment in this age group currently usually is not done in centralized way. |
| Databáze: | OpenAIRE |
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