The Role of Helicobacter Pylori Infection in Idiopathic Thrombocytopenic Purpura in Children
| Autor: | Heba Latif Rizk, Ashraf Mahmoud Radwan, Al Zahraa El Sayed Ahmed |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Helicobacter pylori infection
medicine.medical_specialty business.industry Chronic idiopathic thrombocytopenic purpura 030204 cardiovascular system & hematology medicine.disease Thrombocytopenic purpura Pediatric department 03 medical and health sciences 0302 clinical medicine Immune system Internal medicine medicine Screening method Platelet 030212 general & internal medicine business Adverse effect |
| Zdroj: | The Egyptian Journal of Hospital Medicine. 82:193-198 |
| ISSN: | 2090-7125 |
| DOI: | 10.21608/ejhm.2021.140431 |
| Popis: | Background: Many studies had found obvious relation between helicobacter pylori infection and chronic idiopathic thrombocytopenic purpura; several studies have reported remission of immune thrombocytopenic purpura (ITP) after eradication of a coexistent Helicobacter pylori infection in adults, data in children are limited. Objective: To detect the association of H. pylori infection and idiopathic thrombocytopenic purpura in children and the effect of eradication of the infection on platelet count in these patients. Patients and methods: This study was conducted on 83 chronic idiopathic thrombocytopenic purpura children with age range from 3 to 13 years. They were 46 males 37 females. Also the study included 104 healthy individual with the same range of age. They were 58 males and 46 females as a control group. This was between October 2018 and September 2019 in the Pediatric Hematology and GIT Clinics or inpatients wards of Pediatric Department. Results: Clinical benefit occurred in 31 cases of the 83 chronic ITP (cITP) patients screened; nevertheless, we have a simple, inexpensive, non‐invasive screening method; the adverse events of eradication therapy are negligible, together with an affordable cost, all uncommon attributes among the specific treatments currently available for cITP; therefore it is worthwhile to test for and treat H. pylori infection. Conclusion: Our data showed a prevalence of H. pylori infection in cITP pediatrics that was similar to other studies. We found that successful H. pylori eradication induced platelet response in 37.3% of 83 cases included in our study. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|