Abstract 076: Sex And Stress In Fructose-induced Salt-sensitive Hypertension

Autor:	Autumn Brostek, Nancy J Hong, Ronghao Zhang, Lindsey Kaydo, Nicholas Kluge, Corey Smith, Jeffrey Garvin, Agustin Gonzalez-Vicente
Rok vydání:	2022
Předmět:	Internal Medicine
Zdroj:	Hypertension. 79
ISSN:	1524-4563 0194-911X
Popis:	Proximal tubule fructose metabolism is key to fructose-induced hypertension, but the roles of sex and stress are unclear. We hypothesized that females are resistant to the salt-sensitive hypertension caused by low amounts of dietary fructose compared to males and that the magnitude of the increase in blood pressure (BP) depends, in part, on amplification of the stress response of renal sympathetic nerves. We measured systolic BP (SBP) in rats fed high salt with either no sugar (HS), 20% glucose (GHS) or 20% fructose (FHS) in the drinking water for 7-8 days. FHS increased SBP (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ef6c1c842cdcc92a8191a79376ce1daa https://doi.org/10.1161/hyp.79.suppl_1.076 Zobrazit plný text záznamu