Consequences of Dental Occlusion Enhancement by Means of Metal Crowns on the Animal Model
Autor: | Ana Ispas, Marcela Elisabeta Barbinta Patrascu, Mariana Constantiniuc, Liana Lascu, Antarinia Craciun |
---|---|
Rok vydání: | 2019 |
Předmět: |
business.industry
Dental occlusion Materials Science (miscellaneous) Process Chemistry and Technology General Engineering Dentistry General Chemistry General Medicine General Biochemistry Genetics and Molecular Biology Animal model Materials Chemistry Medicine General Pharmacology Toxicology and Pharmaceutics business |
Zdroj: | Revista de Chimie. 69:3517-3519 |
ISSN: | 2668-8212 0034-7752 |
DOI: | 10.37358/rc.18.12.6782 |
Popis: | The purpose of this study was to determine whether there is a correlation between induced occlusal trauma and the occurrence of oxidative stress in the hippocampus. Twenty Wistar rats were randomized into three experimental groups and one control group. Animals in the experimental group were cemented modified crowns on molars to induce occlusal trauma in 7, 14 and 30 days. To evaluate the oxidative stress, blood was drawn from the hippocampus at 7, 14 and 30 day intervals. Oxidative stress was evaluated using the following specific tests: determination of plasma malondialdehyde and serum glutathione values. The results of the study demonstrate that malocclusion experienced by raising the vertical dimension in rats resulted in significant reductions in antioxidants and increase level of free radicals. |
Databáze: | OpenAIRE |
Externí odkaz: |