Mortality risk and life years lost in young patients with heart failure according ejection fraction. Data from the Swedish Heart failure, National Patient, Cause of Death and Population Registers

Autor: C Basic, A.R Rosengren A, U.D Dahlstrom, M.E Edner, T.Z.S Zverkova Sandstrom, M.S Schaufelberger
Rok vydání: 2020
Předmět:
Zdroj: European Heart Journal. 41
ISSN: 1522-9645
0195-668X
Popis: Background There is a lack of data evaluating excess mortality risk (over that of the general population) and life-years lost in young patients with different heart failure (HF) phenotypes. Purpose To study excess risk for all-cause mortality in patients Methods All patients ≥18 years registered in the national quality register SwedeHF from 2003 to 2014 were included. Patients were divided into ≥55 years and Results In total 60,962 patients, out of whom 3752 50%. Patients with HF50% more often had hypertension (40.6% vs. 29.8%), hypertrophic cardiomyopathy (11.5% vs. 0.7%) and congenital heart disease (7.6% vs. 2.7%), all p>0.001. Cardiovascular death was the most common cause of death in all EF categories (about 55%). In a Cox proportional hazard model, patients with EF >50% had hazard ratio (HR) (95% CI) 10.6 (5.71–19.8), those with EF 40–49% 6.83 (4.43–10.5) and patients with EF50% lost 32.3, 28.7, 26.1, 26.3 and 21.6 “life years” as presented in figure 1. Conclusion HF patients 50% had different coexisting conditions and higher mortality risk, although not significant when compared to patients with EF 50% lost more life years than patients with EF Figure 1 Funding Acknowledgement Type of funding source: None
Databáze: OpenAIRE