Enantiopure Indolizidones and Pyrrolizidones from Maleic Imide

Autor:	Ekkehard Winterfeldt, Peter Nemes, Michael Dockner, Martina G. Otten, Thorsten Meyer
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Enantiopure drug chemistry Yield (chemistry) Regioselectivity Organic chemistry General Chemistry Alkylation Imide Adduct
Zdroj:	Bulletin des Sociétés Chimiques Belges. 103:379-387
ISSN:	0037-9646
Popis:	The alkylated maleic imide adducts of type 3 have been shown to undergo highly regioselective selectride reductions. As with these compounds regioselectivity in further transformations including a thermal retro process translates directly into enantioselectivity, various cyclisation techniques were applied. The advanced cycloadducts obtained led to the enantiopure alkaloid precursors 9, 17, 20 and 25 in very high yield.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ef65b00febd0af8a1d6e7fd26ad1eba7 https://doi.org/10.1002/bscb.19941030711 Zobrazit plný text záznamu