Nanocrystalline copper(II) oxide catalyzed aza-Michael reaction and insertion of α-diazo compounds into N–H bonds of amines

Autor:	Soumi Laha, M. Lakshmi Kantam, Jagjit S. Yadav, Shailendra Jha
Rok vydání:	2009
Předmět:	Chemistry Organic Chemistry Oxide chemistry.chemical_element Heterogeneous catalysis Biochemistry Medicinal chemistry Copper Nanocrystalline material Catalysis Copper(II) oxide chemistry.chemical_compound Drug Discovery Michael reaction Organic chemistry Diazo
Zdroj:	Tetrahedron Letters. 50:4467-4469
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2009.05.059
Popis:	Nanocrystalline copper(II) oxide efficiently catalyzed the conjugate addition of aliphatic amines to α,β-unsaturated compounds to produce β-amino compounds with excellent yields under mild reaction conditions. Similarly, Glycine esters are obtained in good yields by the insertion of α-diazoacetate into N–H bonds of amines. The catalyst is used for three cycles with minimal loss of activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ef5f9c63509457d6af5fcdf59a1cad3c https://doi.org/10.1016/j.tetlet.2009.05.059 Zobrazit plný text záznamu Full Text from ScienceDirect