Effect of buckwheat extract on free radical generation in rabbits administered high-fat diet
| Autor: | B. Gonet, S. Juźwiak, L. Samochowiec, E. Dabrowska‐Zamojcin, S. Tustanowski, M. Katdońska, J. Wójcicki |
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| Rok vydání: | 1995 |
| Předmět: |
Pharmacology
medicine.medical_specialty Antioxidant food.ingredient Triglyceride Cholesterol medicine.medical_treatment Insulin Coconut oil food and beverages Biology Malondialdehyde Rutin chemistry.chemical_compound Endocrinology food Blood serum chemistry Biochemistry Internal medicine medicine lipids (amino acids peptides and proteins) |
| Zdroj: | Phytotherapy Research. 9:323-326 |
| ISSN: | 1099-1573 0951-418X |
| Popis: | In this study the effect of buckwheat extract (BE) on the level of malondialdehyde (MDA), lipids and hormones, and on the concentration of ascorbate free radicals in the liver (compared with rutin) in animals receiving a highfat diet (HFD) was measured. Male mongrel rabbits were randomly divided Into four groups: (1) control, (2) animals given HFD containing cholesterol and coconut oil, (3) rabbits treated with HFD + BE, (4) HFD + rufin, over a period of 12 weeks. The concentration of MDA in rabbits of group 3 (HFD + BE) was slightly but significantly decreased, whilst the number of ascorbate free radicals, examined in vitro, in the liver was markedly elevated. The level of testosterone in rabbit blood serum (group 3) was increased, but the insulin concentration was significantly diminished (in comparison with group 2). The content of total cholesterol and triglyceride in the liver of animals maintained on BE was decreased. Quite distinct superiority of BE, compared with rutin, was shown. |
| Databáze: | OpenAIRE |
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