Cardiac enzyme changes in myxedema coma
| Autor: | P E Hickman, W Silvester, A A Musk, G H McLellan, A Harris |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty biology business.industry Biochemistry (medical) Clinical Biochemistry Myxedema coma Hypothermia medicine.disease chemistry.chemical_compound Enzyme Endocrinology chemistry Plasma enzyme Internal medicine Lactate dehydrogenase medicine biology.protein Creatine kinase Myocardial infarction medicine.symptom Myxedema business |
| Zdroj: | Clinical Chemistry. 33:622-624 |
| ISSN: | 1530-8561 0009-9147 |
| DOI: | 10.1093/clinchem/33.4.622 |
| Popis: | A 74-year-old man with myxedema and hypothermia had increased activities in plasma of creatine kinase (CK; EC 2.7.3.2), aspartate aminotransferase (AST; EC 2.6.1.1), and lactate dehydrogenase (LD; EC 1.1.1.27) and increased proportions of CK-MB (up to 20% of total CK) and LD1 isoenzymes, but no clinical or investigational evidence of associated myocardial infarction. This case illustrates that plasma enzyme activity and isoenzyme profiles in such clinical settings should be interpreted with caution, because increases in CK-MB and LD1 may relate to myxedema coma or hypothermia (or both) rather than to myocardial infarction. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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