The Role of Hepatokines in Cardiovascular Disease
| Autor: | Leonardo Roever, Anaisa Silva Roerver Borges, Resende Es |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Heart disease
business.industry Fatty liver Type 2 Diabetes Mellitus 030209 endocrinology & metabolism Disease medicine.disease Bioinformatics Pathogenesis 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis medicine Metabolic syndrome Endothelial dysfunction business |
| Zdroj: | Journal of Metabolic Syndrome. |
| ISSN: | 2167-0943 |
| Popis: | Non-alcoholic fatty liver disease (NAFLD) is considered a hepatic manifestation of metabolic syndrome, and associated with the risks of developing cardiovascular disease (CVD) and type 2 diabetes mellitus (DM2). A group of liver-derived proteins called hepatokines directly affect the pathogenesis of atherosclerosis by modulating endothelial dysfunction and infiltration of inflammatory cells. In this review we summarize the role of the representative hepatokines in the progression of CVD. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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