A short dipolar cycloaddition approach to γ-lactam alkaloids from cynometra hankei

Autor:	Richard Foster, Colin W. G. Fishwick, Robin E. Carr
Rok vydání:	1996
Předmět:	chemistry.chemical_compound Chemistry Stereochemistry Organic Chemistry Drug Discovery Cynometra hankei Lactam Azomethine ylide Biochemistry Cycloaddition
Zdroj:	Tetrahedron Letters. 37:3915-3918
ISSN:	0040-4039
DOI:	10.1016/0040-4039(96)00688-0
Popis:	The γ-lactam based alkaloid cynometrine has been synthesised in four steps from 1-methyl-imidazole-4-carboxaldehyde. The key step involves an efficient regio-, stereo-, and chemoselective 1,3-dipolar cycloaddition of a dithiolane-fused azomethine ylide.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ef0eca34317c5995e2a902a957d11ee7 https://doi.org/10.1016/0040-4039(96)00688-0 Zobrazit plný text záznamu Full Text from ScienceDirect