Possible role of C60 fullerene in the induction of reproductive toxicity in the freshwater fish, Anabas testudineus (Bloch, 1792)
| Autor: | Nechat Sumi, K. C. Chitra |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
biology Health Toxicology and Mutagenesis Anabas testudineus Ovary General Medicine biology.organism_classification Pollution Enzyme assay Endocrinology medicine.anatomical_structure Internal medicine Toxicity medicine biology.protein Freshwater fish Environmental Chemistry Ecotoxicology Aromatase Reproductive toxicity |
| Zdroj: | Environmental Science and Pollution Research. 27:19603-19615 |
| ISSN: | 1614-7499 0944-1344 |
| Popis: | In recent years, the impact of ultrafine nanomaterials on the aquatic organisms and their ecosystems contributed much concern due to their abundance in environment. Several toxicity studies have reported that nanoparticles induced reproductive stress and resulted in reproductive impairment of fishes. The present study was aimed to investigate the stress-induced toxicity of C60 fullerene nanomaterial on various reproductive parameters of the freshwater fish, Anabas testudineus. Fish were exposed to two sublethal concentrations of fullerene C60, one-tenth (5 mg/L) and one-fifth (10 mg/L) of LC50–96 h, for 4, 7, 15, 30, and 60-day durations. At the end of exposure period, the activities of steroidogenic enzymes, 3β-, and 17β-hydroxysteroid dehydrogenase decreased in the testis and ovary thereby indicated that the nanomaterial affected gonadal steroidogenesis. The level of serum testosterone decreased significantly (p |
| Databáze: | OpenAIRE |
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