One-pot synthesis of 2-aryl-1,2-fused pyrimidones

Autor: Samikannu Ramesh, Pon Saravanakumar, Arvind Mathur, Pirama Nayagam Arunachalam, Ramasamy Duraisamy
Rok vydání: 2017
Předmět:
Zdroj: Journal of Chemical Sciences. 129:329-333
ISSN: 0973-7103
0974-3626
DOI: 10.1007/s12039-017-1244-z
Popis: A facile and versatile method for the synthesis of alicyclic fused pyrimidones from aminoacrylates and lactams in the presence of phosphorous oxychloride is described. The results suggest that this method is widely applicable except for cyclobutyl fused systems. This method gives better yield than the method of condensing aminopyrrolidines with the beta keto esters.
Databáze: OpenAIRE