| Autor: |
Haley, William E., Gilbert, Olivia N., Riley, Robert F., Newman, Jill C., Roumie, Christianne L., Whittle, Jeffrey, Kronish, Ian M., Tamariz, Leonardo, Wiggers, Alan, Morisky, Donald E., Conroy, Molly B., Kovalik, Eugene, Kressin, Nancy R., Muntner, Paul, Goff Jr., David C., SPRINT Study Research Group |
| Rok vydání: |
2016 |
| Předmět: |
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| DOI: |
10.7916/d8xw5scq |
| Popis: |
We examined baseline data from the Systolic Blood Pressure Intervention Trial (SPRINT) to investigate whether medication adherence, measured by the 8-item Morisky Medication Adherence Scale (MMAS-8), was associated with systolic blood pressure (SBP) and whether MMAS-8 score and number of antihypertensive medications interacted in influencing SBP. A total of 8435 SPRINT participants were included: 21.2% had low adherence (MMAS-8: 160 mm Hg in 8.8%. In multivariable regression, medium vs. low adherence weakly associated with lower SBP (odds ratio: 1.17; confidence interval: 1.04, 1.31). SPRINT eligibility criteria should be considered when interpreting results. Efforts to understand and enhance adherence are crucial to improve population health, and using self-report instruments might be considered for predicting treatment adherence and response in future efficacy trials and for identifying patients for adherence support in clinical practice. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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