159 CD 64 as a Diagnostic Marker for Neonatal Infection

Autor:	Giacomo Faldella, M. Casadei Maldini, Elisabetta Tridapalli, Guido Cocchi, S. Gualdi
Rok vydání:	2005
Předmět:	CD64 biology Cell Diagnostic marker Molecular biology Neonatal infection medicine.anatomical_structure Antigen Pediatrics Perinatology and Child Health Immunology medicine biology.protein Antibody Receptor
Zdroj:	Pediatric Research. 58:381-381
ISSN:	1530-0447 0031-3998
DOI:	10.1203/00006450-200508000-00188
Popis:	Background CD64 (Fcgamma-receptor I) is a high-affinity receptor for the Fc-portion of immunoglobulin molecules, normally expressed only by monocytes and to a very low extent by neutrophils. During infection the cytokine-induced activation of neutrophils results in changes in the expression of leucocyte-differentiation antigens with an increase in CD64 levels above the normal cut-off of 6136 antibody-phycoerythrin molecules bound/cell. The aim of this study was to evaluate the diagnostic utility of CD64 expression on neutrophil surface to identify neonatal infection.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::eec2f4465056ae81b52dff78d1b9d90c https://doi.org/10.1203/00006450-200508000-00188 Zobrazit plný text záznamu