Nucleophilic displacement of activated aryl triflates a new synthesis of oxindoles and arylacetic acids

Autor:	Joseph G. Atkinson, Burton K. Wasson, José J. Fuentes, Yves Girard, C. Stanley Rooney, Edward L. Engelhardt
Rok vydání:	1979
Předmět:	chemistry.chemical_compound Nucleophile Chemistry Aryl Yield (chemistry) Organic Chemistry Drug Discovery Organic chemistry Biochemistry Medicinal chemistry Dimethyl malonate
Zdroj:	Tetrahedron Letters. 20:2857-2860
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(01)86434-0
Popis:	2-Nitroaryl triflates undergo efficient base-catalyzed nucleophilic displacement by dimethyl malonate anion to yield dimethyl nitroarylmalonates, which subsequently are converted in high yields to nitroarylacetic acids and oxindoles.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::eebd14f8cf7f93ecf9201cfd06ac3ec4 https://doi.org/10.1016/s0040-4039(01)86434-0 Zobrazit plný text záznamu