Indium(III)-Catalyzed Addition of Diethyl Acetamidomalonate to Terminal Alkynes: An Efficient Approach to β-Branched α-Amino Acids

Autor: Peter G. Blazecka, Ji Zhang, Mark Lovdahl, Paul Angell
Rok vydání: 2007
Předmět:
Zdroj: The Journal of Organic Chemistry. 72:6606-6609
ISSN: 1520-6904
0022-3263
Popis: The indium(III)-catalyzed Markovnikov addition of active methylene compounds to terminal alkynes has been expanded further to include diethyl acetamidomalonate. This reaction has been studied, and a practical approach to β-branched α-amino acids was developed.
Databáze: OpenAIRE