ChemInform Abstract: A Three-Step and Enantioselective Synthesis of (-)-(S)- or (+)-(R)-2-(Furan-3-yl)-3,6-dihydro-2H-pyrans
Autor: | Arrigo Scettri, Margherita De Rosa, Arlette Solladié-Cavallo |
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Rok vydání: | 2010 |
Předmět: | |
Zdroj: | ChemInform. 31 |
ISSN: | 1522-2667 0931-7597 |
DOI: | 10.1002/chin.200024132 |
Popis: | Enantiomerically enriched (3-furyl)-2-pyran derivatives, key-intermediates in the synthesis of the pharmacophoric pyranofuranone system of the bioactive natural products manoalide and cacospongionolide B, are easily accessible by a rapid sequence involving a chiral allylation and a ring closing metathesis reaction. |
Databáze: | OpenAIRE |
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