ChemInform Abstract: A Three-Step and Enantioselective Synthesis of (-)-(S)- or (+)-(R)-2-(Furan-3-yl)-3,6-dihydro-2H-pyrans

Autor: Arrigo Scettri, Margherita De Rosa, Arlette Solladié-Cavallo
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 31
ISSN: 1522-2667
0931-7597
DOI: 10.1002/chin.200024132
Popis: Enantiomerically enriched (3-furyl)-2-pyran derivatives, key-intermediates in the synthesis of the pharmacophoric pyranofuranone system of the bioactive natural products manoalide and cacospongionolide B, are easily accessible by a rapid sequence involving a chiral allylation and a ring closing metathesis reaction.
Databáze: OpenAIRE