Correlations of Oxidized Low Density Lipoprotein with Insulin, Leptin and Risk of Cardiovascular Disease in a group of Diabetic Obese Tunisian Women
| Autor: | O. Belhadj, Faika Ben Mami, Mohamed Chiheb Ben Rayana, Hajer Aounallah Skhiri, Fethi Ben Slama, Wala Gaaloul Helali |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
business.industry Cholesterol Leptin Insulin medicine.medical_treatment Blood lipids medicine.disease chemistry.chemical_compound Insulin resistance Endocrinology chemistry Diabetes mellitus Low-density lipoprotein Internal medicine Medicine lipids (amino acids peptides and proteins) business Body mass index |
| Zdroj: | Journal of Obesity & Weight Loss Therapy. |
| ISSN: | 2165-7904 |
| DOI: | 10.4172/2165-7904.1000279 |
| Popis: | At the obese diabetic ones, there’s a disturbance of lipid parameters from where the installation of an insulin resistance responsible for the development of non-insulin-dependent diabetes. Objectives: Our objectives were to evaluate the levels of insulin, leptin and oxidized LDL, and to search the link which could exist between these parameters and obesity represented by the body mass index (BMI >30 kg/m2). Methods: We proportioned the rate in total cholesterol, triglycerides, blood glucose, insulin, leptin, cholesterol LDL, cholesterol HDL and oxidized LDL at 53 obese women diabetic not carrying pathologies other than the diabetes type 2 and obesity compared to 21 witnesses who theirs are paired according to the age. Results: Our results shows that levels of total cholesterol, triglycerides, blood glucose, insulin, leptin, cholesterol LDL and oxidized LDL were higher in obese women with non-insulin-dependent diabetes mellitus compared with control group. Moreover a positive and significant correlation between body mass index and blood glucose (r=0.408, p=0.002), leptin (r=0.436, p=0.001), insulin (r=0.403, p=0.003), cholesterol LDL (r=0.365, p=0.007) and oxidized LDL (r=0.632, p |
| Databáze: | OpenAIRE |
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