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Objectives: This study is aimed to examine the potential association between childhood trauma (CT) and personality traits among unaffected first-degree relatives (FDR, children or siblings of patients) of patients with major depressive disorder (MDD). Methods: The study consists of three groups: total 85 patients with MDD, 35 FDRs and 89 healthy control individuals (HC). The Childhood Trauma Questionnaire (CTQ) was used to assess childhood trauma and the Eysenck Personality Questionnaire used to assess personality traits. Results: By comparison made in personality traits, MDD patients exhibits some significant disparities to FDR and HC (pConclusion: CT was associated with N, P and L, with a closer relation to N in unaffected FDR. Besides, the type of CT, the most relevant to N, was discovered to be EN. Thus, FDR of MDD who experienced CT should be prioritized. Key words: childhood trauma; personality; major depressive disorder; first-degree relatives |
